Osirix and its free counterpart Horos are very useful and afforable DICOM viewing softwares. You can use this software to create 3D Surface rendering which can be exported as polygonal mesh models. The problem is that these models have very dense meshes that are not practical for routine use in 3D animation software.
Adding Zbrush to the workflow allows the controlled remeshing of these models. Before importing into Zbrush open ends should be capped. Once in Zbrush the model can be dynameshed to remove interior and redundant sections of the model. Then hole defects or sections of thin bone can be repaired as desired using the pinch and inflate brushes.
A final pass using Zremesher, reduces the polygon count to a desired level.
In the example shown, a the number of polygons in a model of the bones, kidneys, ureters, and bladder was reduced approximately 14%. Of course the number of polys could be reduced more, based on the desired look and application (3D render versus VR or AR).